B-cell lymphoma ADCT-402-105

Study #ADCT-402-105

A Phase 1b Open-Label Study to Evaluate the Safety and Anti-cancer Activity of Loncastuximab Tesirine in Combination With Other Anti-cancer Agents in Patients With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma (LOTIS-7)

Description
The primary objective of this study is to characterize the safety and tolerability of loncastuximab tesirine in combination with polatuzumab vedotin, glofitamab, or mosunetuzumab, and to identify the maximum tolerated dose (MTD) and/or recommended dose for expansion (RDE) for the combinations.

Sponsor: ADC Therapeutics S.A.

Principal Investigator: Dr. Tara Graff

Interested in this trial? Email [email protected].

Back To Clinical Trials NCI Database Entry